By J. Lemerle, M. F. Tournade, C. Patte (auth.), Professor Gianni Bonadonna, Professor Georges Mathé, Professor Sydney E. Salmon (eds.)
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Additional info for Adjuvant Therapies and Markers of Post-Surgical Minimal Residual Disease II: Adjuvant Therapies of the Various Primary Tumors
In this series we have not analyzed pre amputation values of alkaline phosphatase and cannot therefore use this for prognostication. Pre- and postadriamycin determinations of the enzymes, however, were done in 52 cases. In general, the initial and subsequent levels of alkaline phosphatase are of value in predicting the recurrence of osteosarcoma. Four patterns of alkaline phosphatase changes were observed during the course of the disease: (a) normal level initially remaining normal during therapy, (b) elevated initially with a drop to normal following therapy, (c) elevated initially with succeeding values intermittently low and high, and (d) normal initially with subsequent elevation.
1, 369-381 (1977) 9. : Interferons: Anti-neoplastic drugs? Blut 35, 277-288 (1977) 10. , Jakobsson, P. : Acute infections in interferon-treated patients with osteosarcoma: Preliminary report of a comparative study. J. Infect. Dis. 133, A245-248 (1976) 11. , Jakobsson, P. : Interferon treatment of osteogenic sarcoma - a clinical trial. Fogarty Int. Center Proc. 28, 377-381 (1977) 12. : Effect of human leukocyte interferon on the growth of human osteosarcoma cells in tissue culture. Int. J. Cancer 19, 468-473 (1977) Current Results With a Combined Treatment Approach to Localized Ewing's Sarcoma M.
291, 998-1000 (1974) 4. Cortes, E. , Holland, J. , Wang, J. J. : Adriamycin (NSC-123127) in 87 patients with osteosarcoma. Cancer Chemother. Rep. (Part 3) 6, 305-313 (1975) 5. Cortes, E. , Wanka, J. : Adriamycin (NSC-123127) cardiotoxicity: a clinicopathologic correlation. Cancer Chemother. Rep. (Part 3), 6, 215-225 (1975) 6. Cortes, E. , Holland, J. : Amputation and adriamycin in primary osteosarcoma: a 5-year report. Cancer Treat. Rep. 62, 271-277 (1978) 7. Enneking, R. W. : "Skip" metastases in osteosarcoma.
Adjuvant Therapies and Markers of Post-Surgical Minimal Residual Disease II: Adjuvant Therapies of the Various Primary Tumors by J. Lemerle, M. F. Tournade, C. Patte (auth.), Professor Gianni Bonadonna, Professor Georges Mathé, Professor Sydney E. Salmon (eds.)